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Found 9 Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50379241'
TargetMonoglyceride lipase(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataKi:  4.00E+4nMAssay Description:Non-competitive inhibition of human recombinant MAGL assessed as 7-hydroxycoumarin level using umbelliferyl arachidonate as substrate by luminescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  275nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  280nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  288nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed