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Found 3 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50274741'
TargetMu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50274741(CHEMBL4126470)
Affinity DataIC50:  0.350nMAssay Description:Displacement of [125I]-DAMGO from mouse Flag-tagged mu-opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50274741(CHEMBL4126470)
Affinity DataIC50:  1.60nMAssay Description:Compound was tested for competitive blocking of guinea pig ileal smooth muscle strip contraction to cholecystokinin-8 (CCK-8) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50274741(CHEMBL4126470)
Affinity DataEC50:  0.120nMAssay Description:Tested for thromboxane antagonist potency (pA2) against U 44619 induced platelet aggregation using human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed