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Found 4 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM97712'
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97712(US8476271, 18 | US8846929, 358 | US9145408, 358)
Affinity DataKi:  1.60E+3nM ΔG°:  -33.1kJ/molepH: 7.4 T: 2°CAssay Description:In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97712(US8476271, 18 | US8846929, 358 | US9145408, 358)
Affinity DataKi:  1.60E+3nMpH: 7.4Assay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.2nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20mg membrane protein/w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97712(US8476271, 18 | US8846929, 358 | US9145408, 358)
Affinity DataKi:  1.60E+3nM ΔG°:  -33.1kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97712(US8476271, 18 | US8846929, 358 | US9145408, 358)
Affinity DataEC50:  1.78E+4nMpH: 7.4 T: 2°CAssay Description:Mu-Opioid Receptor Functional Assay Procedures: [35S]GTP gamma S functional assays were conducted using freshly thawed mu-receptor membranes. Assay r...More data for this Ligand-Target Pair
In DepthDetails US Patent