Found 3 Enz. Inhib. hit(s) with Target = 'Multidrug resistance-associated protein 1' and Ligand = 'BDBM50174854'
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against MRP1-mediated LTC4 uptake into membrane vesicles from HeLa-T5 cells expressing MRP1More data for this Ligand-Target Pair
Affinity DataEC50: 93nMAssay Description:Reversal of MRP1-mediated doxorubicin-resistance in human HeLa-T5 cells assessed as reduction of doxorubicin IC50 percent by halfMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Inhibitory activity against MRP1 in HeLa-T5 cellsMore data for this Ligand-Target Pair