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Found 10 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50030196'
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  174nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based beta-arrestin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataIC50:  1.59E+3nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of xanomeline-induced response by BRET based beta-arrestin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein engagement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataEC50:  35nMAssay Description:Positive modulatory activity at human M1 receptor expressed in HEK293T cells assessed as effect on carbachol-induced response by BRET based Gq protei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataEC50:  120nMAssay Description:Positive modulatory activity at human M1 receptor expressed in HEK293T cells assessed as effect on xanomeline-induced response by BRET based Gq prote...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataEC50:  102nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataEC50:  263nMAssay Description:Positive modulatory activity at human M1 receptor expressed in HEK293T cells assessed as effect on xanomeline-induced response by BRET based Gq prote...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataEC50:  191nMAssay Description:Positive modulatory activity at human M1 receptor expressed in HEK293T cells assessed as effect on carbachol-induced response by BRET based Gq protei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030196(CHEMBL3354065)
Affinity DataEC50:  832nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based beta-arrestin engagement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed