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Found 2 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50084425'
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance Respiratory

US Patent
LigandPNGBDBM50084425(CHEMBL3426704 | US9394275, I-25)
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance Respiratory

US Patent
LigandPNGBDBM50084425(CHEMBL3426704 | US9394275, I-25)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressing CHO-K1 cells incubated for 60 mins or 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed