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Found 3 Enz. Inhib. hit(s) with Target = 'Myeloperoxidase' and Ligand = 'BDBM312264'
TargetMyeloperoxidase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM312264(1-[2-(Aminomethyl)-4-(trifluoromethyl)benzyl]-2-th...)
Affinity DataIC50:  40nMAssay Description:The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM312264(1-[2-(Aminomethyl)-4-(trifluoromethyl)benzyl]-2-th...)
Affinity DataIC50:  40nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM312264(1-[2-(Aminomethyl)-4-(trifluoromethyl)benzyl]-2-th...)
Affinity DataIC50:  40nMAssay Description:MPO: The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent