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Found 4 Enz. Inhib. hit(s) with Target = 'N-acylethanolamine-hydrolyzing acid amidase' and Ligand = 'BDBM50439654'
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50:  140nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50:  140nMAssay Description:Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50:  140nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50:  148nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed