Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'NACHT, LRR and PYD domains-containing protein 3' and Ligand = 'BDBM50530842'
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  300nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  300nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  300nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 30 mins followed by A...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50530842(CHEMBL4559751)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed