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Found 3 Enz. Inhib. hit(s) with Target = 'NACHT, LRR and PYD domains-containing protein 3' and Ligand = 'BDBM612339'
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612339(BDBM612451 | BDBM612452 | N'-(4-fluoro-2,6- diisop...)
Affinity DataIC50:  24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612339(BDBM612451 | BDBM612452 | N'-(4-fluoro-2,6- diisop...)
Affinity DataIC50:  120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612339(BDBM612451 | BDBM612452 | N'-(4-fluoro-2,6- diisop...)
Affinity DataIC50:  3.00E+3nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent