Found 3 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM50276140' TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University
Curated by ChEMBL
Cornell University
Curated by ChEMBL
Affinity DataIC50: >8.30E+4nMAssay Description:Inhibition of human SIRT1 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University
Curated by ChEMBL
Cornell University
Curated by ChEMBL
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human SIRT1 expressed in Escherichia coli BL21 using H3K9AcWW as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University
Curated by ChEMBL
Cornell University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human SIRT1 deacetylase activity using acetylated H3K9 as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
