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Found 2 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM50439674'
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human sirtuin 1 using fluorogenic HDAC substrate incubated for 20 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT1 (1 to 747 end residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed