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Found 1 Enz. Inhib. hit(s) with Target = 'NEDD8-activating enzyme E1 regulatory subunit' and Ligand = 'BDBM50318907'
TargetNEDD8-activating enzyme E1 regulatory subunit(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed