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Found
1
Enz. Inhib. hit(s) with Target = 'NEDD8-conjugating enzyme UBE2F' and Ligand = 'BDBM321009'
Target
NEDD8-conjugating enzyme UBE2F
(Homo sapiens (Human))
Taiho Pharmaceutical
US Patent
Ligand
BDBM321009
(4-Amino-5-[2-(5-benzyloxypyrimidin-2-yl)ethynyl]-7...)
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Affinity Data
IC50: 5.10nM
Assay Description:
A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...
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Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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Ligand Info
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Details
US Patent
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