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Found 3 Enz. Inhib. hit(s) with Target = 'Neuromedin-K receptor' and Ligand = 'BDBM357795'
TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM357795((3,4-difluorophenyl)(3-(3- methyl-1,2,4-thiadiazol...)
Affinity DataKi:  170nMAssay Description:NK-2/NK-3: The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 recep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM357795((3,4-difluorophenyl)(3-(3- methyl-1,2,4-thiadiazol...)
Affinity DataKi:  170nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM357795((3,4-difluorophenyl)(3-(3- methyl-1,2,4-thiadiazol...)
Affinity DataKi:  170nMAssay Description:NK-2/NK-3: The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 recep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent