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Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM125047'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125047(US8772511, 4 | US9714242, 22)
Affinity DataKi: <1nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125047(US8772511, 4 | US9714242, 22)
Affinity DataKi:  2.10nM ΔG°:  -46.0kJ/molepH: 7.4 T: 2°CAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125047(US8772511, 4 | US9714242, 22)
Affinity DataKi:  2.10nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent