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Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50149146'
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50149146((S)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo...)
Affinity DataKi:  13nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149146((S)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo...)
Affinity DataKi:  13nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149146((S)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo...)
Affinity DataIC50:  26nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed