Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50190785'
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50190785(CHEMBL378349 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190785(CHEMBL378349 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]MLA from alpha7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50190785(CHEMBL378349 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed