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Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50250186'
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50250186(4-(3-Acetyl-5-(4-chlorophenyl)-2-methyl-1H-pyrrol-...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50250186(4-(3-Acetyl-5-(4-chlorophenyl)-2-methyl-1H-pyrrol-...)
Affinity DataEC50:  1.20E+3nMAssay Description:Allosteric modulator activity at alpha7 nAChR in human IMR32 cells assessed as stimulation of agonist-induced intracellular calcium level by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed