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Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50319944'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319944(2-methyl-5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319944(2-methyl-5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human alpha7 nACHR expressed in Xenopus oocyte assessed as activation of current by voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed