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Found 4 Enz. Inhib. hit(s) with Target = 'Neutrophil collagenase' and Ligand = 'BDBM50092158'
TargetNeutrophil collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Affinity DataIC50:  2.25E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Affinity DataIC50:  2.25E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Affinity DataIC50:  3.50E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent