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Found
1
Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM105227'
Target
Neutrophil elastase
(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Ligand
BDBM105227
(US8580800, 4)
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Affinity Data
IC50: 10nM
pH: 7.4 T: 2°C
Assay Description:
The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...
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