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Found 2 Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM50448645'
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50448645(CHEMBL3127512)
Affinity DataIC50:  750nMAssay Description:Inhibition of C-terminal His-tagged human full-length NAMPT expressed in Escherichia coli Rosetta DE3 using nicotinamide as substrate preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50448645(CHEMBL3127512)
Affinity DataKd:  860nMAssay Description:Binding affinity to NAMPT (2 to 491) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed