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Found 4 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, endothelial' and Ligand = 'BDBM29234'
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  8.50E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  8.50E+4nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  8.52E+4nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM29234(CHEMBL481815 | US9090589, 6 | aminopyridine-pyrrol...)
Affinity DataKi:  8.52E+4nM ΔG°:  -23.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair