Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, endothelial' and Ligand = 'BDBM50124535'
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50124535(1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50124535(1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50124535(1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed