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Found 3 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible' and Ligand = 'BDBM50091805'
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091805(2-amino-4,6-dimethylpyridine | 4,6-Dimethyl-pyridi...)
Affinity DataIC50:  45nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091805(2-amino-4,6-dimethylpyridine | 4,6-Dimethyl-pyridi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091805(2-amino-4,6-dimethylpyridine | 4,6-Dimethyl-pyridi...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed