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Found 3 Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50083231'
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083231(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of [125I]-Tyr14-nociceptin binding to human Opioid receptor like 1 (opioid receptor like 1) in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083231(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Affinity DataIC50:  20nMAssay Description:Antagonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083231(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed