Affinity DataKi: 1.90nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.286nMAssay Description:Displacement of [3H]-NC from human ORL1 receptor expressing HEK-293 cell membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 0.219nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.93nMAssay Description:Binding of compound to cell membranes expressing human ORL1 receptor in HEk-293 cells using [32S]-GTP-gammaSMore data for this Ligand-Target Pair