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Found 4 Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50106477'
TargetNociceptin receptor(MOUSE)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50106477(CHEMBL265801 | FGGFTGARKSARKLADE | Phe-GGFTGARKSAR...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106477(CHEMBL265801 | FGGFTGARKSARKLADE | Phe-GGFTGARKSAR...)
Affinity DataIC50:  0.286nMAssay Description:Displacement of [3H]-NC from human ORL1 receptor expressing HEK-293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106477(CHEMBL265801 | FGGFTGARKSARKLADE | Phe-GGFTGARKSAR...)
Affinity DataEC50:  0.219nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106477(CHEMBL265801 | FGGFTGARKSARKLADE | Phe-GGFTGARKSAR...)
Affinity DataEC50:  1.93nMAssay Description:Binding of compound to cell membranes expressing human ORL1 receptor in HEk-293 cells using [32S]-GTP-gammaSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed