Affinity DataKi: 0.480nMAssay Description:Binding affinity to human NOP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Affinity to nociceptin receptors on mouse forebrain membranes by [3H]NC-NH2 displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Displacement of [3H]nociceptin from recombinant ORL1 receptor expressed in COS7 cells by competitive receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Binding affinity to ORL1 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]nociceptin from human ORL1-Galpha fusion receptor in COS7 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]nociceptin from recombinant ORL1 receptor expressed in COS7 cells by competitive receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in HEK293 cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to human NOP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.91nMAssay Description:Activity at human ORL1-Galpha fusion receptor in COS7 cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at recombinant ORL1 receptor expressed in COS7 cells assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0920nMAssay Description:Binding affinity to recombinant ORL1 receptor expressed in COS7 cells by saturation binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at recombinant ORL1 receptor expressed in COS7 cells assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair