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Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear factor NF-kappa-B p105 subunit' and Ligand = 'BDBM367259'
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Immunetarget

US Patent
LigandPNGBDBM367259(US10226464, Compound 27)
Affinity DataIC50: <500nMAssay Description:DNA binding reaction (20 μL) was carried out in 1×DNA Binding Buffer (10 mM Tris, 40 mM NaCl, 1 mM EDTA, 4% glycerol) with 10 nM c-Rel protein a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Immunetarget

US Patent
LigandPNGBDBM367259(US10226464, Compound 27)
Affinity DataIC50: <5.00E+3nMAssay Description:NFκB/Jurkat/GFP transcriptional reporter cell line was obtained from SBI System Biosciences. NF-κB/Jurkat/GFP™ Reporter cells (5×105 cells)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent