Found 3 Enz. Inhib. hit(s) with Target = 'Nuclear factor erythroid 2-related factor 2' and Ligand = 'BDBM50539550'
Affinity DataEC50: 360nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 360nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction assessed induction of Nrf2 nuclear translocationMore data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMAssay Description:Activation of Nrf2 in human spinal cord astrocytes assessed as increase in glutathione level after 20 hrsMore data for this Ligand-Target Pair