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Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-alpha' and Ligand = 'BDBM50369033'
TargetNuclear receptor ROR-alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50369033(CHEMBL4167096)
Affinity DataIC50:  6.20E+3nMAssay Description:Inverse agonist activity at His6-tcs-human RORalpha LBD assessed as inhibition of biotinylated PGC1alpha (130 to 154 residues) peptide recruitment in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50369033(CHEMBL4167096)
Affinity DataIC50: >3.30E+4nMAssay Description:Agonist activity at His6-tcs-human RORalpha LBD assessed as stimulation of biotinylated PGC1alpha (130 to 154 residues) peptide recruitment incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed