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Found
1
Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM491717'
Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM491717
(5-(4-(Difluoromethoxy)-6-((4,4,4-trifluoro-2-methy...)
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Affinity Data
Kd: 3.30nM
Assay Description:
For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR...
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Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
PC cid
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Details
US Patent
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