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Found
1
Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM497906'
Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM497906
((5R,8S)-8-(2-(3-(difluorophenyl)-1H- pyrazol-1-yl)...)
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Affinity Data
IC50: 5.5nM
Assay Description:
50 mM HEPES buffer (pH 7.4); 150 mM NaCl; 1 mM DTT; 5 mM MgCl2; 0.01% BSA; 5% DMSO; 0.6 ug/mL RORc receptor; 6 nM 25-[3H]hydroxycholesterol. For NSB ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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