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Found 3 Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM334957'
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334957(US11040966, Example 5.217 | US9732075, Example 5.2...)
Affinity DataIC50:  15nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334957(US11040966, Example 5.217 | US9732075, Example 5.2...)
Affinity DataIC50:  15nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334957(US11040966, Example 5.217 | US9732075, Example 5.2...)
Affinity DataIC50:  98nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent