Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM50314676'
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314676((4-(6-fluoroquinazolin-2-yl)-1,4-diazepan-1-yl)(5-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to OX1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314676((4-(6-fluoroquinazolin-2-yl)-1,4-diazepan-1-yl)(5-...)
Affinity DataIC50:  36nMAssay Description:Antagonist activity at OX1 receptor assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed