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Found 2 Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM50384429'
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50384429(CHEMBL2031492 | US9896452, Example 137)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at OX1 receptor expressed in CHO cells assessed as inhibition of OXA-stimulated intracellular calcium mobilization after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50384429(CHEMBL2031492 | US9896452, Example 137)
Affinity DataIC50:  3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
In DepthDetails US Patent