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Found 4 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM294756'
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM294756(2-(4,6-Dimethylpyrimidin-2-yl)-5-{[3-fluoro-2-(1H-...)
Affinity DataKi:  8nMAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM294756(2-(4,6-Dimethylpyrimidin-2-yl)-5-{[3-fluoro-2-(1H-...)
Affinity DataKi:  8nMAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM294756(2-(4,6-Dimethylpyrimidin-2-yl)-5-{[3-fluoro-2-(1H-...)
Affinity DataKi:  8nMAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM294756(2-(4,6-Dimethylpyrimidin-2-yl)-5-{[3-fluoro-2-(1H-...)
Affinity DataKi:  587nM ΔG°:  -35.6kJ/moleT: 2°CAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent