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Found 6 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50384416'
TargetOrexin receptor type 2(Homo sapiens (Human))
Sosei Heptares

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  631nMAssay Description:Displacement of [3H]4-(2,6-Difluoro-4-methoxybenzyl)-2-(5,6-dimethoxypyridin-3-yl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide from human wild-typ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Sosei Heptares

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  835nMAssay Description:Binding affinity to human OX2 receptor expressed in CHO cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Sosei Heptares

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Sosei Heptares

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  3.78E+3nMAssay Description:Binding affinity to human OX2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Sosei Heptares

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataIC50:  8.35E+5nMAssay Description:Antagonist activity at human OX2R expressed in CHOK1 cells by Syto62 probe based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Sosei Heptares

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataIC50:  8.35E+5nMAssay Description:Antagonist activity at human OX2R expressed in CHOK1 cells by Syto62 probe based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed