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Found 5 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50438822'
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50438822(CHEMBL2413367)
Affinity DataKi:  417nMAssay Description:Displacement of (2S)-N-(2-pyrrol-1-ylphenyl)-1-[2-[1-(tritritiomethyl)benzimidazol-2-yl]sulfanylacetyl]pyrrolidine-2-carboxamide from human OX2 recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50438822(CHEMBL2413367)
Affinity DataKi:  417nMAssay Description:Binding affinity to human OX2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50438822(CHEMBL2413367)
Affinity DataIC50:  417nMAssay Description:Antagonist activity at OX2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50438822(CHEMBL2413367)
Affinity DataIC50:  417nMAssay Description:Antagonist activity at orexin-2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50438822(CHEMBL2413367)
Affinity DataIC50:  417nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed