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Found 3 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM65030'
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM65030(US9475819, 181)
Affinity DataKi:  700nM ΔG°:  -36.9kJ/moleT: 2°CAssay Description:HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM65030(US9475819, 181)
Affinity DataKi:  770nMAssay Description:Binding affinity to human OX2RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM65030(US9475819, 181)
Affinity DataKi: >1.00E+4nM ΔG°: >-30.0kJ/moleT: 2°CAssay Description:HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...More data for this Ligand-Target Pair
In DepthDetails US Patent