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Found 5 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM97407'
TargetOrexin receptor type 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataKi:  1.30nMAssay Description:The inhibition constant (ki) is determined using a radioligand assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H](S)-N-(2-(1H-pyrrol-1-yl)phenyl)-1-(2-(1-methyl-1H-benzo[d]imidazol-2-ylthio)acetyl)pyrrolidine-2-carboxamide from human OX2R exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human OX2R expressed in CHOK1 cells assessed as reduction in orexin A-induced calcium flux preincubated followed by orexin A a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Rattus norvegicus (Rat))
TBA

US Patent
LigandPNGBDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataIC50:  28nMT: 2°CAssay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataIC50:  28nMAssay Description:Antagonist activity against human OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intercellular Ca2+ mobilization by FLIPR a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed