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Found 14 Enz. Inhib. hit(s) with Target = 'Oxytocin receptor' and Ligand = 'BDBM50029649'
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]-oxytocin from oxytocin receptor in human uterus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity was evaluated by measuring the displacement of [3H]-OT (oxytocin) from specific binding sites in uterine tissue obtained from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity for cloned human oxytocin receptor (OT-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  6.30nMAssay Description:Displacement of 3[H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity against cloned human oxytocin receptor from human embryonic kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity for human oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  10nMAssay Description:Ability to displace [3H]oxytocin from human OT receptor (hOT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  19nMAssay Description:Binding affinity against oxytocin receptor (rOTr) in DES pretreated rat uterineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  19nMAssay Description:Binding affinity was evaluated by measuring the displacement of [3H]-OT (oxytocin) from specific binding sites in uterine tissue obtained from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  19nMAssay Description:Binding affinity for rat uterine oxytocin receptor (rOTr)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-oxytocin from oxytocin receptor in rat uterus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataKi:  20nMAssay Description:Antagonist activity at human cloned oxytocin receptor by cell based beta lactamase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataIC50:  640nMAssay Description:Compound was tested for displacement of 3[H] oxytocin from rat OT receptor (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50029649(1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...)
Affinity DataEC50:  4.60nMAssay Description:Activity at human oxytocin receptor expressed in CHO cells by NFAT-luciferase gene reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed