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Found 12 Enz. Inhib. hit(s) with Target = 'P-selectin' and Ligand = 'BDBM50450369'
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory activity of compound was determined against Selectin P binding by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against blocking of Selectin P during migration of inflammatory cells to inflammatory siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Selectin P bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Mus musculus)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50: >1.00E+6nMAssay Description:Blocking activity using seletin-IgG chimeras in a Selectin P competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against human chimeric Selectin P-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50:  1.30E+6nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in P-selectin; value ranges from 1.3-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50:  2.00E+6nMAssay Description:In vitro inhibitory activity against sialyl Lewis X expressing HL60 cell binding Selectin PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50: >3.00E+6nMAssay Description:Tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay A) in P-selectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50:  3.40E+6nMAssay Description:Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin P-IgG fusion proteinsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50:  5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin P and HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50:  5.50E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin P and HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)
Affinity DataIC50:  5.50E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin P and HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed