Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM237018'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM237018(US9388197, 20)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:Cells were grown to confluency in adherent culture at 37° C. in a humidified 5% CO2 incubator (split 1/5 every 3-4 days with DMEM, 10% FCS, 1% Pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM237018(US9388197, 20)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced calcium mobilization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM237018(US9388197, 20)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced calcium mobilization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed