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Found 2 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50359212'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359212(CHEMBL1923307)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359212(CHEMBL1923307)
Affinity DataIC50:  121nMAssay Description:Antagonist activity at P2X7 receptor in rat whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed