Found 4 Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase A' and Ligand = 'BDBM172718'
Affinity DataIC50: 9.70nMAssay Description:The PPlase activity of recombinant CypA or D, produced by thrombin cleavage of GST-CypA or D, was determined by following the rate of hydrolysis of N...More data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Pure His-cyclophilins were immobilized and covalently stabilized on the NTA sensor chip according to the protocol described in Thermo-kinetic analysi...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Pure His-cyclophilins were immobilized and covalently stabilized on the NTA sensor chip according to the protocol described in Thermo-kinetic analysi...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:All ITC experiments for the ester series compounds were carried out at 25° C. on a MicroCal Auto iTC200 (GE Healthcare) instrument. The buffer used i...More data for this Ligand-Target Pair