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Found 2 Enz. Inhib. hit(s) with Target = 'Phenylalanine--tRNA ligase alpha/beta subunit' and Ligand = 'BDBM231670'
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231670(5-(3-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50:  60nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231670(5-(3-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50:  1.00E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed