Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2' and Ligand = 'BDBM50054405' TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 660nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 660nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
