Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2' and Ligand = 'BDBM50469035' TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia
Curated by ChEMBL
University Of East Anglia
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia
Curated by ChEMBL
University Of East Anglia
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SHIP2 (unknown origin) assessed as decrease in PIP2 production using PtdIns(3,4,5)P3 as substrate preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
